This room is located on the first floor in the western wing. As of the July 19th, 2017 Build the room has a pink and white scheme. It is slightly cluttered. A couple of lights and an air conditioner hang from the ceiling. There are three cots with white curtains between them on the western side of the room. In the middle of the room, there is a table with four chairs surrounding it.
In the northern corner of the room is an eye chart, a scale, and a height measure.
The placeholder nurse always stands in the northeastern corner. The syringe is located on a desk behind her. There is also a tall glass cabinet on the eastern side.
On the southern side lays a large couch and cork board with a hand washing sign.
The room used to have a white floor with light grey walls, but the office was eventually renovated to a brighter color scheme, complete with a beige hardwood floor.
This is supposed to be the room where the nurses will work. The current nurse there cannot be interacted with, as she has no AI yet. The syringe and tranquilizer are both located in this room for kidnapping. The tranquilizer is located on a desk to the right of the placeholder nurse.
YandereDev has stated that in future builds of the game, Yandere-chan will have to find a way to take the tranquilizer and the syringe without the nurse noticing, such as Yandere-chan poisoning another student's food non-lethally to distract the future nurses. While a nurse is distracted, the player will be able to steal the equipment.
- The room was renovated in the November 15th, 2015 Build.
- This room is a store bought model from the Unity Asset Store named Japanese School Infirmary Set.
- The room was renamed from "Nurse's Office" to "Infirmary" in the July 12th, 2016 Build.