This room is located on the first floor in the western wing. As of the July 19th, 2017 Build the room has a pink and white scheme. It is slightly cluttered. A couple of lights and an air conditioner hang from the ceiling. There are three cots with white curtains between them on the western side of the room. In the middle of the room, there is a table with four chairs surrounding it.
In the northern corner of the room is an eye chart, a scale, and a height measure. The syringe is located on a desk next to them. There is also a tall glass cabinet on the eastern side.
On the southern side lays a large couch and cork board with a hand washing sign.
The room used to have a white floor with light grey walls, but the office was eventually renovated to a brighter color scheme, complete with a beige hardwood floor.
This is supposed to be the room where the nurses will work. The syringe and tranquilizer are both located in this room for kidnapping. The tranquilizer is located on a desk to the right of Nasu.
In the future, Yandere-chan will have to find a way to take the tranquilizer and the syringe without Nasu noticing, such as Yandere-chan poisoning another student's food non-lethally to distract the future nurses. While Nasu is distracted, Yandere-chan will be able to steal the equipment.
- The room was renovated in the November 15th, 2015 Build.
- This room used to be a store bought model from the Unity Asset Store named Japanese School Infirmary Set.
- The room was renamed from "Nurse's Office" to "Infirmary" in the July 12th, 2016 Build.
- However, the HUD still says "Nurse's Office".